By trigger wire, you both are referring to the red "power on" wire, which will turn on the box with very little voltage (which is why some dash lights will keep it running with the switch off), but MSD still indicates that the box needs a full 12 volts to this wire. May well be splitting hairs, but I feed my MSD 12 volts, it's easy enough to do.
Anyway, I'm doing just what you're asking about - using an MSD 6A box with a Duraspark distributor. I love it, the engine fires right off even when cold, and once it's been warmed up I only have to bump the starter and it starts right up. I haven't gotten my carb jetted right yet, but on my Buick 350 I was able to lean out the primary side settings after installing an MSD box, and the performance is up (according to my butt-dyno)
On the Ranchero, I've got an underhood fuseblock mounted beside the radiator on the driver's side, so the MSD main power leads are nice and short, and fused. I used the MSD-to-DuraSpark distributor adapter, confirming the wire polarity (it was ok), and ran the distributor trigger wires back along the block to the coil, then over to the body, and up/over the shock tower to the MSD box. The wires from the MSD box to the coil run back alongside the trigger wires to the coil, along with the "power on" red wire, which hooks to the Ford wire from the ignition switch. I replaced the old coil / ignition feed resistor wire under the dash so I've got full voltage to the "power on" wire.
Here's the wiring on the engine: Blue arrow point to the distributor trigger wires, The MSD adapter is a short piece from behind the fuel pump to right behind the coil, where I connected it to an MSD extension harness that the rear blue arros is point at. The Yellow arrow points to the MSD-to-coil wires, and the Green arrow points to the "power on" connection.
Here's the wiring on the fender: the red MSD box (which I want to camouflage), the Red arrow points to the underhood fusebox, and the Blue arrows point to the trigger and coil wire bundles going over the shock tower.
Since I took these photos, I've hidden the distributor wires under the motor mount and tidied up the wire routing so that they're hardly noticeable. If there wasn't a big red box on the fender, you wouldn't know it wasn't a points ignition!
Hope this helps!