I think there are a lot of possible solutions here, based on what one wants from the engine.
In my case I'll be looking for a nice streetable setup, with a little punch at the top end, plus, I'll be using this car for a lot of highway driving too. So, I figure that I might be better off with a single 2 barrel setup, or 2 single barrel units, with a very minor progressive linkage.
I'd go with the 3 singles almost entirely based on the cool factor, but there do seem to be some questions regarding drivability, and maintenance.
If you're thinking about dual 2 barrel, why not find an appropriate 4 barrel for the application. The adjustability of Holley 4 barrels, especially the 4150 series with a jetted, mechanical secondary plate leaves very little to be desired, except of course the cool factor. You can also take a 4160, vacuum secondary and convert the plate to a jetted one.
There is just something appealing to me about 1 barrel carbs for some reason, and I think that's why I liked the triple setup, although now that I've seen what's involved, I'd probably just build my own adaptor and linkages.
Jim