Tip 1, measure the width of the internal crank case.
The Chrylser Slant six was very wide, and can be overstroked with the stock rods 2.25" rod journal welded out to 4.50" from the stock 4.175". A few grinds to the sides, and care full checking of the cam clearnace, sweet! With a 100 thou over bore, 260 cubes from a 225 cuber, a 16% improvement in torque with no other mods. Like going from a 302 to a 351!
The 223, what was the longest stroke it ran? It's likely the 300 will take 4.375" stroke.
In Aussie, the little 186 cube holden engines with very tight crank space of less than 9", could take an offset ground Falcon crank, and get a 235 cube monster with Holden stock rods. A 26% boost in capapcity.
Tip 2:
The Holden block was gouged out in the pan area like an ancient glacier path, the cam was ground down for conrod clearnace, and the rods bolts and rod caps were curved with a linisher to create space. A spare block, some time, and allow for reducing a block to scrap when you cut through a water gallery, but a 335 looks possible.
There are some nice long Honda rods, with smaller journals, which would work real nice. Frenctown Flyer noted that the drag racing set had experiemented with them for reducing rubbing speed of the bearings, or destroking. Most of the time you offset grind to upstroke the throw of the crank, you loose strength in the crank. The fillet radii around each of the six big ends can be reworked to a 20 to 30 thou radius, and create a stronger stoker crank than one that doesn't have a prepared fillet radius. The strength is all in the surface, not so much in the overlap and journal size. It's doubtfull you could make a stroker as strong as the stock 3.98".
Last point is that an offset grind on a cast 300 crank with a 1.88" rod journal will only yield about 4.21" tops. 322 cubes with 30 over pistons.
With a steel crank, if you can trace one, you can weld and maintain the stock 2.124" journal size, and still get 4.375". If it doesn't hit the camshaft. 335 cubes with +30's. A 7 to 11% increase.