Something to remember / consider.
Non full race 4Vs are progressive, primaries opening first followed by secondaries. Opening of secondaries can be either mechanical or vacuum actuated. Basically the same as a multi carb set-up with all venturi grouped together.
Too much throttle opening drops the vaccum too low to draw fuel in to the venturis. Secondaries, be they additional carbs or venturis, should open when needed.
Think of your progressive multi carb setup as a progressive 4V in sections, center carb is the primary, end carbs are the secondaries.
Cruise on the primary, go for full power on the secondaries.