Curtis, the holley 350 cfm 2300 is rated that figure @ 3 hg. To convert that carb to 1.5 hg where all 4 barrel carbs are rated is 247 cfm, a 500 holley would go to 353 cfm @ 1.5 hg.
I guess holley rates them for a huge engine application where at full throttle you never reach close to zero hg. Using both carbs on a small six cylinder engine you will be closer to the flow ratings for a 4 barrel carb.
I don't know the rating system for the autolite carbs. Just compare venturi diameter. The 350 holley is 1 3/16", the 500 is 1 3/8".
Hope this helps, william