I started out with the 32/36 back when my engine was basically a stock '66 200 with a Duraspark ignition, headers, and a COMP 260h cam. It was on the 2-1 adapter. I liked it a lot, except I felt like I needed to floor it if I wanted to get the car to move, so I tried the 38/38. Definitely felt more power in normal driving, but I could never get a steady idle out of it... for me it was difficult to tune, and was constantly swapping jets to try to get it to be somewhat reliable.
After I upgraded to a modified large log head, I did a direct mount with the Autolite 2100 (1.08). It's hard to compare to the Webers because I swapped the head at the same time, but it's really a great carb. Reliable, smooth, no flat spots... and never had to mess with jets. Just put it on, turned the 2 mix screws, and according to my A/F gauge it's pretty much dialed in all the time.
-Nick