For that Hp level , you want as much compression as pump gas will allow , so shoot for about 10-10.5-1 I am not a fan of the DUI , it has its good points , but for the money a Recurved Duraspark with a MSD 6al box will out perform and cost less , port the head and add larger valves , an adjustable valve train and a Solid cam , the one that is in my 250 would work great unfortunatly is a Crane unit that is no longer made , CI has some that will work and I strongly say to use a Solid Grind , NOT a Hyd , its free torque an hp ( and no you don't have too constantly adjust the valves with today metalurgy) ( as much as your budget allows a direct mount 2brl a 350 Holley is what I would suggest , with the Bowel facing the valve cover , yes you will need to fab a cable throttle , again a High stall converter will be needed , unless you only want a sound and looks combo as compared to one that performs as well as it sounds and looks , a Manual Valve Body in your Trans will eliminate the need for a Vacuum modulator and a kick down and the Factory shifter can be modified to work slick ( if you go that route I can fill you in ) rear gears shoud be in the 3.5-3.80 range for , Headers and a good dual system is a must , I think to have the total package will be in the 5000.00 dollar range but you could build the engine and add the externals as money allows