I have spoken with four different cam manufactures, including Isky when we were at SEMA last fall. All suggested a dual pattern cam in applications using the OZ heads or Offy trips due to the increases in CFMs on the intake side. Applications with the stock log and a single carb would not see much benefit in dual patterns. I agree with 67 Falcon, the Comp 260 would be my choice for most daily driven applications.
I am currently developing a cam line suited to OZ and Offy applications, but can match any cam grind from any manufacturer. The nice thing about custom ground cams is the ability to tailor the cam to the specific application. I haven't got a firm price yet but they should be in the range of $110-120.