Get Dave Emanuel's Holley book from the early 1980's. There is no subsitute.
It coveres the set-up of the accelerator pump, the squirters and the placing of the spring on the cam. There are a few different types of plastic cam, which profiles the discharge.
I could give you a long rambling talk, but it would only be a poor copy.
Other Holley books are simpler and a bit more user friendly, but none better than his.
(Only other things I'd add is
1.Never tune a car by braile. You can't randomly try a bunch of settings unless you understand what it is your trying to do.
2.A Holley with dirty fuel is worse than useless. Any issues with accelerator pump set-up are best takled when the main jets and power valve are set.
3.A 350 cfm carb is only a 130-150 flywheel hp device, tops. A Weber ADM 34 is infact a better carb.
4.If you want push-you in the back response, take a 2-5 mpg fuel consumption drop and get a 500 cfm carb.)
5.If you drop the fuel pressure to 2.5 to 3 psi rather than 5 to 6 psi, the fuel consumption will improve. You may find this requires bigger squirters, a different cam position.
6.Power valves should be a lower vacuum number than what it would be on the Chev/AMC/International V8's the 350 cfm carb was first designed for in the early sixties. A 10.5 power valve will be running too rich on a high performance six cylinder car, even the 8.5 may be too rich on the highway. Go for a 6.5 for a start.)