Howdy Chicken
Yes, your Autolite 1100 carb through '67 , with the Spark Control Valve is designed to work with your stock Load-a-Matic Distributor.
Yes, it will run if the SCV is plugged, and Yes, it will run if the vacuum line is connected to full manifold vacuum- BUT- it will not run as designed, it will not work as well, Your plugs will show signs of peppering at highway speeds- an indication of too much advance.
A Load-a-Matic distributor will only work properly when hooked to a SCV on an 1100 Autolite carb. You might want to red the "Stickies" at the top of this forum. When working as designed, it is not a bad system. Please read emphasis on the "Working as designed" part.
"Working as designed" means that;
*there are no vacuum leaks
*the SCV is working.
*the vacuum cannister on the L-a-M distributor is not leaking and is working.
*all vacuum lines are in good, tight shape.
*the mechanism inside the distributor is clean and free moving. All springs are in place and functioning.
Good Luck.
Adios, David