I'd strongly suggest you tune the Holley 350 cfm carb and ignition you have now.
The problem with running
a Holley 2300 series (#7748 350cfm 1.19"/#4412 500 cfm 1.38")
an Autolite 2100 or Motorcraft 2150 (sizes from 0.98/1.01/1.02/1.08/1.14/1.21/1.23/1.33 or 190/240/245/287/300/351/356/424 cfm)
is that each are set up for V8's between 221 to 390 cubic inches (3.6 to 6.6 liters) and not 200 to 250 cubic inches (3.3 to 4 .1 liters) I6 like our cars are.
The fuel delivery curve needs adjustment to suit the needs of a small I6. Without work on
1.Idle Air Bleeds,
2.well tubes,
3.power valve channel restrictions,
4.power valves and
5.jetting,
any carb you get will cost performance compared to the Holley you have now.
The Autolite and Motorcraft carbs cost performance because they are high signal carbs which are generally cost about 10% in performance over a Holley, with a similar gain if fuel economy.
What the best Holley 2-bbl tuners do is enlarge the air bleeds with a kit, and adjust the power valve and power vale channel restrictions, and then check with an air fuel meter of oxygen sensor.
By all means if you are unhappy with your 2-bbl Holley, go get an Autolite, but the money spent on adjusting the air fuel ratio via those five methods above will work. and give you a good result.