Howdy Fred and All:
Q- "Do I make changes on the carb for 95 octane gas ?"
A- No. But, take note of the performance of your engine, as well as the initial advance setting of the distributor. It is a good idea, for performance and economy, to use as much initial advance as your engine can safely use, without pinging or knocking, when lugging the engine. Does your car have a manual transmission or an automatic? The initial advance setting are different for each. Depending on your elevation and climate, you should be able to use up to an additional 5 degrees of initial advance. The extra advance will give your engine a noticeable increase in both mileage and power.
Does your engine have a stock 1966 Load-O-Matic distributor?
And welcome to THE FORUM.
Adios, David