Here is a little info which will perhaps help you if you are into reading camshafts rather than tea leaves or hops. It covers what happens to the pressure in the cylinder when you wind up the camshaft duration.
These are some tables which I have compiled which are based on the calculations used in many engineering manuals on recipricating engines. The are part of the calculation of Brake Effective Mean Pressure, which governs how much horspower an engine can develop. Since you can't cheet the laws of physics, and the formulae used are written elseware in books like Practical Gas Flow and Phil Irvings "Tunning For Speed" book on motor cycle engineering, I want go into the trigonimetery used to calculate it...yet. People like StrangeRanger and XT500, Aussie7Mains and others will go over this with a fine tooth comb, so I'll refrain from shoving my hands in a mouth that has two feet in it already
Consider yourself spared from more dribble.
MORE DRIBBLE:
Case One :Using a 250 cubic inch Aussie 2V or similar head with:
*a slightly bigger than normal 62 cc combustion chamber,
**12 cc piston dish,
***41 thou thick composite gasket (7.15 cc),
**** a 25 thou (4.36 cc) below the cylinder deck register
{which is much closer to a zero deck than the US 250},
*****and the stock 681.49 cc piston displacement
you get an 8.97:1 static compression ratio.
Given that the stroke is 3.91 inches, and the hypothetical "stock" cam has a valve event of 15/53 52/19 for the otto cylce, the effective compression the piston actually sees can be calculated. You use a formulae which works out the distance of effective compression stroke using trig, the stroke, the valve event, and the length of the rod (which is irrelevent...a 6.275 inch rod verses the stock 5.885 rod makes a 0.2% lower effective compression). It's always less than the total stroke. You then plug this calculated value into the compression ratio formulae, and presto, you got the effective compression. The red value is the one used for calculation purposes, I think. (It's been a while since I've used it, and the reference manual is at work).
"Stock" cam 15/53 52/19, 182/185, 248/251 means intake cylce is 15/53 degrees, exhast is 52/19 degrees, 50 thou valve duration at intake is 182 deg, exhast duration is 185 deg, and total duration is 248 intake, and 251 exhast.
This has an effective stroke of 3.264", and gives an effective compression of 7.654:1. This is a benchmark figure which shouldn't be gone under for longer duration cams. The static compression needs to be raised to ensure the on cam characteristics are maintained. If you go more than 20% below 7.654:1 for any subsequent cam combo on this engine, you risk unfavorable brake specific fuel consumption characteristcs, and performance and economy will go down hill.
So I have just grabed at random six hydraulic cams, and three mechanical cams. Here are the amounts of compression that need to be added for each one:-
"Stage 1 Stock hyd" cam 15/53 52/19, 182/185, 248/251, 7.654:1 effective, okay as it is at 8.97:1 already. The Baseline
"Stage 2 hydraulic" cam 27/65 68/30, 202/208, 272/278, 6.781:1 effective, 13% loss, needs to be 10.125:1 static to run best.
"Stage 3 hydraulic" cam 32/70 73/35, 212/218, 282/288, 6.475:1 effective, 18% loss, needs to be 10.603:1 static to run best.
"Stage 4 hydraulic" cam 36/76 79/39, 222/228, 292/298, 6.089:1 effective, 25.7% loss, needs to be 11.275:1 static to run best.
"Stage 5 hydraulic" cam 40/80 81/41, 236/238, 300/302, 5.958:1 effective, 28.5% loss, needs to be 11.523:1 static to run best.
"Stage 6 hydraulic" cam 42/83 83/47, 243/248, 305/310, 5.823:1 effective, 31% loss, needs to be 11.791:1 static to run best.
"Stage 4 mechanical" cam 37/77 79/41, 234/240, 294/300, 6.089:1 effective, 25.7% loss, needs to be 11.275:1 static to run best.
"Stage 5 mechanical" cam 43/85 88/46, 244/250, 308/314, 5.483:1 effective, 39.6% loss, needs to be 12.523:1 static to run best.
"Stage 6 mechanical" cam 46/86 89/49, 254/260, 312/318, 5.414:1 effective, 41.4% loss, needs to be 12.682:1 static to run best.
Summary: Any hi-duration cam will need bulk compression increases to run best. It's unlikely any one would consider using race fuel to run such high static compression ratios. It is clear that a compromise between the theory and the practice will have to made. Any thingover 18% loss should be countered with increased compression, so long as detonation doesn't result.
Case Two :Using a late 200 cubic inch US Log 1V or similar head with:
*a normal 62 cc combustion chamber,
**zero cc piston dish,
***41 thou thick composite gasket (7.15 cc),
**** a 69 thou (12.00 cc) below the cylinder deck register
*****and the stock 544.847 cc piston displacement
you get an 7.714:1 static compression ratio.
Calculations for the same cams above with a smaller engine, and less compression. Close to a stock post 71 engine. Stroke is 3.126, connecting rod is 4.71 inches long.
"Stage 1 Stock hyd" cam 15/53 52/19, 182/185, 248/251, 6.747:1 effective, okay as it is at 7.714:1 already. The Baseline
"Stage 2 hydraulic" cam 27/65 68/30, 202/208, 272/278, 6.065:1 effective, 11.1% loss, needs to be 8.581:1 static to run best.
"Stage 3 hydraulic" cam 32/70 73/35, 212/218, 282/288, 5.818:1 effective, 16.0% loss, needs to be 8.946:1 static to run best.
"Stage 4 hydraulic" cam 36/76 79/39, 222/228, 292/298, 5.504:1 effective, 22.6% loss, needs to be 9.456:1 static to run best.
"Stage 5 hydraulic" cam 40/80 81/41, 236/238, 300/302, 5.395:1 effective, 25.1% loss, needs to be 9.647:1 static to run best.
"Stage 6 hydraulic" cam 42/83 83/47, 243/248, 305/310, 5.285:1 effective, 27.7% loss, needs to be 9.848:1 static to run best.
"Stage 4 mechanical" cam 37/77 79/41, 234/240, 294/300, 5.504:1 effective, 22.6% loss, needs to be 9.456:1 static to run best.
"Stage 5 mechanical" cam 43/85 88/46, 244/250, 308/314, 4.999:1 effective, 35.0% loss, needs to be 10.410:1 static to run best.
"Stage 6 mechanical" cam 46/86 89/49, 254/260, 312/318, 4.941:1 effective, 36.6% loss, needs to be 10.534:1 static to run best.
Summary: Any hi-duration cam will need bulk compression increases to run best, as before. In this case, the engine runs a low compression. In this instance, it is quite likely someone reconditioning an engine may elect to use these recomended figures with the Stage 4 and below cams, with no detonation setting in. Again any thing over 18% loss should be countered with increased compression, so long as detonation doesn't result. The cam maker suggested just this. Low stages don't need modification. Above Stage 3, compression upgrades are needed.
These are some tables which I have compiled which are based on the calculations used in many engineering manuals on recipricating engines. The are part of the calculation of Brake Effective Mean Pressure, which governs how much horspower an engine can develop. Since you can't cheet the laws of physics, and the formulae used are written elseware in books like Practical Gas Flow and Phil Irvings "Tunning For Speed" book on motor cycle engineering, I want go into the trigonimetery used to calculate it...yet. People like StrangeRanger and XT500, Aussie7Mains and others will go over this with a fine tooth comb, so I'll refrain from shoving my hands in a mouth that has two feet in it already

Consider yourself spared from more dribble.
MORE DRIBBLE:
Case One :Using a 250 cubic inch Aussie 2V or similar head with:
*a slightly bigger than normal 62 cc combustion chamber,
**12 cc piston dish,
***41 thou thick composite gasket (7.15 cc),
**** a 25 thou (4.36 cc) below the cylinder deck register
{which is much closer to a zero deck than the US 250},
*****and the stock 681.49 cc piston displacement
you get an 8.97:1 static compression ratio.
Given that the stroke is 3.91 inches, and the hypothetical "stock" cam has a valve event of 15/53 52/19 for the otto cylce, the effective compression the piston actually sees can be calculated. You use a formulae which works out the distance of effective compression stroke using trig, the stroke, the valve event, and the length of the rod (which is irrelevent...a 6.275 inch rod verses the stock 5.885 rod makes a 0.2% lower effective compression). It's always less than the total stroke. You then plug this calculated value into the compression ratio formulae, and presto, you got the effective compression. The red value is the one used for calculation purposes, I think. (It's been a while since I've used it, and the reference manual is at work).
"Stock" cam 15/53 52/19, 182/185, 248/251 means intake cylce is 15/53 degrees, exhast is 52/19 degrees, 50 thou valve duration at intake is 182 deg, exhast duration is 185 deg, and total duration is 248 intake, and 251 exhast.
This has an effective stroke of 3.264", and gives an effective compression of 7.654:1. This is a benchmark figure which shouldn't be gone under for longer duration cams. The static compression needs to be raised to ensure the on cam characteristics are maintained. If you go more than 20% below 7.654:1 for any subsequent cam combo on this engine, you risk unfavorable brake specific fuel consumption characteristcs, and performance and economy will go down hill.
So I have just grabed at random six hydraulic cams, and three mechanical cams. Here are the amounts of compression that need to be added for each one:-
"Stage 1 Stock hyd" cam 15/53 52/19, 182/185, 248/251, 7.654:1 effective, okay as it is at 8.97:1 already. The Baseline
"Stage 2 hydraulic" cam 27/65 68/30, 202/208, 272/278, 6.781:1 effective, 13% loss, needs to be 10.125:1 static to run best.
"Stage 3 hydraulic" cam 32/70 73/35, 212/218, 282/288, 6.475:1 effective, 18% loss, needs to be 10.603:1 static to run best.
"Stage 4 hydraulic" cam 36/76 79/39, 222/228, 292/298, 6.089:1 effective, 25.7% loss, needs to be 11.275:1 static to run best.
"Stage 5 hydraulic" cam 40/80 81/41, 236/238, 300/302, 5.958:1 effective, 28.5% loss, needs to be 11.523:1 static to run best.
"Stage 6 hydraulic" cam 42/83 83/47, 243/248, 305/310, 5.823:1 effective, 31% loss, needs to be 11.791:1 static to run best.
"Stage 4 mechanical" cam 37/77 79/41, 234/240, 294/300, 6.089:1 effective, 25.7% loss, needs to be 11.275:1 static to run best.
"Stage 5 mechanical" cam 43/85 88/46, 244/250, 308/314, 5.483:1 effective, 39.6% loss, needs to be 12.523:1 static to run best.
"Stage 6 mechanical" cam 46/86 89/49, 254/260, 312/318, 5.414:1 effective, 41.4% loss, needs to be 12.682:1 static to run best.
Summary: Any hi-duration cam will need bulk compression increases to run best. It's unlikely any one would consider using race fuel to run such high static compression ratios. It is clear that a compromise between the theory and the practice will have to made. Any thingover 18% loss should be countered with increased compression, so long as detonation doesn't result.
Case Two :Using a late 200 cubic inch US Log 1V or similar head with:
*a normal 62 cc combustion chamber,
**zero cc piston dish,
***41 thou thick composite gasket (7.15 cc),
**** a 69 thou (12.00 cc) below the cylinder deck register
*****and the stock 544.847 cc piston displacement
you get an 7.714:1 static compression ratio.
Calculations for the same cams above with a smaller engine, and less compression. Close to a stock post 71 engine. Stroke is 3.126, connecting rod is 4.71 inches long.
"Stage 1 Stock hyd" cam 15/53 52/19, 182/185, 248/251, 6.747:1 effective, okay as it is at 7.714:1 already. The Baseline
"Stage 2 hydraulic" cam 27/65 68/30, 202/208, 272/278, 6.065:1 effective, 11.1% loss, needs to be 8.581:1 static to run best.
"Stage 3 hydraulic" cam 32/70 73/35, 212/218, 282/288, 5.818:1 effective, 16.0% loss, needs to be 8.946:1 static to run best.
"Stage 4 hydraulic" cam 36/76 79/39, 222/228, 292/298, 5.504:1 effective, 22.6% loss, needs to be 9.456:1 static to run best.
"Stage 5 hydraulic" cam 40/80 81/41, 236/238, 300/302, 5.395:1 effective, 25.1% loss, needs to be 9.647:1 static to run best.
"Stage 6 hydraulic" cam 42/83 83/47, 243/248, 305/310, 5.285:1 effective, 27.7% loss, needs to be 9.848:1 static to run best.
"Stage 4 mechanical" cam 37/77 79/41, 234/240, 294/300, 5.504:1 effective, 22.6% loss, needs to be 9.456:1 static to run best.
"Stage 5 mechanical" cam 43/85 88/46, 244/250, 308/314, 4.999:1 effective, 35.0% loss, needs to be 10.410:1 static to run best.
"Stage 6 mechanical" cam 46/86 89/49, 254/260, 312/318, 4.941:1 effective, 36.6% loss, needs to be 10.534:1 static to run best.
Summary: Any hi-duration cam will need bulk compression increases to run best, as before. In this case, the engine runs a low compression. In this instance, it is quite likely someone reconditioning an engine may elect to use these recomended figures with the Stage 4 and below cams, with no detonation setting in. Again any thing over 18% loss should be countered with increased compression, so long as detonation doesn't result. The cam maker suggested just this. Low stages don't need modification. Above Stage 3, compression upgrades are needed.