Howdy Mike and All:
The exhaust manifolds are all interchangeable, BUT: (Don't ya jsut hate big butts?)
1960 - '62 manifolds use a flat gasket to the head pipe, and hav a 1.75" outlet.
'63 and later manifolds use an asbestos donut and a fire wall seal to the head pipe and have a 2" outlet. '65 and later manifolds are cast significantly heavier, with gusseting is weak areas.
Beginning is '68 exhaust manifolds begin to sprout bungs for taps for emissions stuff. Later years got even worse. To the point where '80s manifolds have a design which has a fast burn cat converter attached directly to the manifold.
There has been talk about a larger/better 250 design. I have never (yet) seen one that is any different than the 200s for the same year.
My advice is to use a '65 to '68 exhaust manifold. Make sure there are no cracks or flaw, have it flat milled and use an exhaust manifold gasket to attach it.
Adios, David