Unscientific scorners reply."Nature abours a vaccum".
The correct vaccum would only be obtained if the individual load of fuel was subjected to a small chamber which could be placed under a vaccum.
A 500 hp car would need to be able to place fuel( 27 cc per second, or 0.44 US gals per minute) into an 'ideal vaccum chamber'. Then it would have to be given a positive pressure in order to pass into the combustion chamber. Extra work would need to be done to do this, as vaccum pumps are very hard to keep working on a constant, reliable basis. It's much easier to pressurize than to evacute a chamber.
The details are somewhat cloudy to me, and I can't undestand how up to 165 to 195 pounds per square inch of peak combustion pressure could have a slug of negative pressurized vapour injected into the engine.
Pressure zones move from the heigher to the lower. You'd have to make a prechamber engine, or some kind of statified charge engine, and then blow up or heat the gas in a steep change in pressure. A frozen intake charge would pack more stuff into the engine, a prevapourized engine would loose power becasue there is less stuff in the combustion chamber.
A real head bender, DC!