Even though I'm in Nu Zealand, and half a world away, I'll state my reputation on the fact that with two sixty jets, and a totally stock engine, you'll get by with a 500 cfm Holley.
The little 2 liter engines run up to 6500 rpm with a 500 cfm 2-bbl carb at 3.0 " Hg. It may produce 138 hp.The actual airflow demand on one of these little four bangers is 122*6500 all divided by 3456, or 229.5 cfm. At a 85% volumetric effciency, it would shift 195 cfm of air. The peak air speed through a couple of venturis totalling about 0.020624 square feet is 157.5 feet per second, fairly low. At a highway cruise, the car runs at about 3250 rpm, or needing only 115 cfm, or 79 ft/sec of air flow. Peak manifold vaccum at wide open throttle is about 0.46" Hg
A big 250 six, stock as a rock, can pull up to 4500 rpm with a good carb. It may only kick out 110 or so pnies, even with a 500 cfm carb. The 250 has an airflow demand of about ((250*4500)/3456)*0.75, or 244 cfm, since it has only about 75 % volumetric efficiency. This is a gas speed of 197 feet per second at these revs. At its normal 2250 rpm, it flows 122 cfm, or 99 feet per second of air, if volumetric efficiency was the same throughout the rev range. Peak manifold vaccum at wide open throttle is about 0.73" Hg
I know you can say anything you like with numbers, but a 500 cfm carb, jetted properly, will work just fine on a 250. The big 250 can suck a rat up an 8 ft down pipe backwards!