To the individual who indicated he/she wants to run 30 lbs of boost...
Is that a number you think you want to run because you think it sounds impressive or have you run some fashion of turbocharged 300 before and think you can run that much boost? I'd have a hard time believing you'll keep head gaskets in that thing with anywhere near that much boost, head studs, the block o-ringed and all. You're going to hurt something.
Something to keep in mind...boost pressure (psi) is, to a degree, indicative of the restriction in the intake tract (everything between the turbocharger and the intake valve). Take any given turbocharger and stick it on a stock 300 and, for the sake of this example, let's say you see 15 psi of boost on a pressure gauge. Now, take that combination apart and port the cylinder head (increasing flow, reducing restriction and reducing turbulent areas), port-match the intake manifold to the cylinder head (again, reducing turbulence and decreasing restriction in airflow), etc., etc., and put it all back together, with the same camshaft, etc. After it's back together, the combination (properly jetted/fueled) will make more power but yet you'll see less actual boost on the gauge. Why? You've reduced the "restrictiveness" of the intake tract and, at the same time, increased the efficiency of the system.