On a 96 you have mass-air so the rules are a bit different. You will need to have your mass air meter re-calibrated for the new injectors. You can either use your stock regulator and have the meter recalibrated for your new injectors working at the higher pressure of the 300's fuel system, adapt a regulator from a 302 and have the meter calibrated for the new injectors that pressure or use an adjustable regulator and have the meter recalibrated at a probable set pressure. FWIW I could not find an adjustable regulator that could be fitted to the rails of a '96, they are substantially different from the older S/D trucks.
Why are you changing the injectors? Are you making other modifications to the engine? If you're not doing other work, the bigger injectors may not be worth the effort. The 300 is limited as much by the stock head and cam as it is by the fuel system. Unless you re-work the head and get more valve lift and/or duration, you're not going to increase the HP simply by adding bigger injectors.