You'll want an adapter to fit your cylinder head. The bore will measure 1.5" for a small-log (early) head or 1.75" for a large-log (late) head for the 200 and then the 250. Vintage Inlines sells both flavors of adapters for Weber carburetors.
As old as our engines are, it's not uncommon for parts to be switched around. The previous owner of my Mustang had no idea that the car had a 250 head and I wasn't aware of it when I bought the car. At the time of purchase, I was looking for a solid car for a V8 swap. Once I got some guidance from the guys on this forum, I figured out what I had and how to make it work. Now I'm interested in keeping the six.
My reasons for putting the Weber 38 in place of the stock Autolite 1100 copy that was mounted on the car were due primarily to the increased capacity for air given the 250 head, headers, and a 2.25" exhaust that I put on the car. The previous owner was trying to make the stock carb work on the large-log manifold without an adapter by hoping to fill the extra space at the bore with gasket and goop. This made for a huge vacuum leak and very poor performance-it barely ran at all. In fact, so much extra fuel was escaping into the exhaust that he grenaded the muffler on the car. The fuel system was completely trashed. The second pic is of the inside of the original carb.
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Get back to us on which jets you'll be running with your new Weber 38. That's good information for anyone else considering a swap on a similar engine.